别名:CT2.2应用:WB,IHC
反应种属:Human
规格:50μl/100μl
Description |
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Members of the BAGE gene family encode antigens that are recognized by cytotoxic T lymphocytes and are also known as CT (cancer/testis) antigens. Generated by juxtacentromeric shuffling of the MLL3 gene, the ancestral BAGE gene was expanded by acrocentric exchanges and/or juxtacentromeric movements.Generally, BAGE proteins are silent in all normal tissues with the exception of testis. BAGE2 and BAGE 3 (B melanoma antigen 2 and 3, respectively), also known as Cancer/testis antigen 2.2 and 2.3 (respectively), are 109 amino acid secreted proteins that are expressed in 22% of melanomas, lung and bladder carcinomas, and are also expressed in normal testis tissue. Like the genes encoding MAGE proteins, BAGE genes are most likely silenced by DNA methylation and/or chromatin compaction in normal tissues other than testis. |
Specification | |
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Aliases | CT2.2 |
Swissprot | Q86Y30 |
WB Predicted band size | 12 kDa |
Host/Isotype | Rabbit IgG |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Synthetic peptide of human BAGE2 |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Application | |
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WB | 1/200-1/1000 |
IHC | 1/25-1/100 |
ELISA | 1/5000-1/10000 |
Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane: A375 cell lysate, Primary antibody: P06051(BAGE2 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 90 seconds | |
The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P06051(BAGE2 Antibody) at dilution 1/20. (Original magnification: ×200) |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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