Rabbit Polyclonal Antibody to BCA3

包装: 1G|100G|500G|1KG|100KG

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别名:Breast cancer-associated gene 3 protein; PKA-interacting protein; AKIP1;
应用:WB,IHC
反应种属:Human
规格：50μl/100μl

Description
Enhances NF-kappa-B transcriptional activity by regulating the nuclear localization of the NF-kappa-B subunit RELA and promoting the phosphorylation of RELA by PRKACA. Regulates the effect of the cAMP-dependent protein kinase signaling pathway on the NF-kappa-B activation cascade.Kitching R., Biochim. Biophys. Acta 1625:116-121(2003).Amid C., Cytogenet. Cell Genet. 93:284-290(2001).Ota T., Nat. Genet. 36:40-45(2004).

Description

Enhances NF-kappa-B transcriptional activity by regulating the nuclear localization of the NF-kappa-B subunit RELA and promoting the phosphorylation of RELA by PRKACA. Regulates the effect of the cAMP-dependent protein kinase signaling pathway on the NF-kappa-B activation cascade.Kitching R., Biochim. Biophys. Acta 1625:116-121(2003).Amid C., Cytogenet. Cell Genet. 93:284-290(2001).Ota T., Nat. Genet. 36:40-45(2004).

Specification
Aliases	Breast cancer-associated gene 3 protein; PKA-interacting protein; AKIP1;
Entrez GeneID	56672;
Swissprot	Q9NQ31
WB Predicted band size	26kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthesized peptide derived from internal of human BCA3.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Application
WB	1/500-1/3000
IHC	1/50-1/100

	Western blot analysis of extracts from Jurkat cells, using BCA3 antibody P42115.
	Immunohistochemistry analysis of paraffin-embedded human heart tissue using BCA3 antibody P42115.