Rabbit Polyclonal Antibody to BCL-2(Phospho-Thr56)

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别名:Bcl-2, PPP1R50
应用:IHC
反应种属:Human
规格：50μl/100μl

Description
Suppresses apoptosis in a variety of cell systems includingfactor-dependent lymphohematopoietic and neural cells. Regulates cell death bycontrolling the mitochondrial membrane permeability. Appears to function in a feedbackloop system with caspases. Inhibits caspase activity either by preventing the release ofcytochrome c from the mitochondria and/or by binding to the apoptosis-activatingfactor (APAF-1).

Description

Suppresses apoptosis in a variety of cell systems includingfactor-dependent lymphohematopoietic and neural cells. Regulates cell death bycontrolling the mitochondrial membrane permeability. Appears to function in a feedbackloop system with caspases. Inhibits caspase activity either by preventing the release ofcytochrome c from the mitochondria and/or by binding to the apoptosis-activatingfactor (APAF-1).

Specification
Aliases	Bcl-2, PPP1R50
Entrez GeneID	596;
Swissprot	P10415
WB Predicted band size	26kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Peptide sequence around phosphorylation site of threonine 56(G-H-T(p)-P-H) derived from Human BCL-2.
Formulation	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.