中文 
别名:Bcl-2-interacting killer, Apoptosis inducer NBK, BIP1, BP4, BIK, NBK应用:WB,IHC
反应种属:Human, Mouse
规格：50μl/100μl
| Description |
|---|
| The Bik protein is known to interact with cellular and viral survival-promoting proteins, such as BCL2 and the Epstein-Barr virus in order to enhance programmed cell death. Because its activity is suppressed in the presence of survival-promoting proteins, this protein is suggested as a likely target for antiapoptotic proteins. This protein shares a critical BH3 domain with other death-promoting proteins, BAX and BAK. |
| Specification | |
|---|---|
| Aliases | Bcl-2-interacting killer, Apoptosis inducer NBK, BIP1, BP4, BIK, NBK |
| Entrez GeneID | 638 |
| Swissprot | Q13323 |
| WB Predicted band size | 18.0kDa |
| Host/Isotype | Rabbit IgG |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | This Bik BH3 Domain antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-74 amino acids from human Bik BH3 Domain. |
| Formulation | Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Application | |
|---|---|
| WB | 1/1000-1/2000 |
| IHC | 1/100-1/500 |
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All lanes : Anti-hBik-BH3 at 1:2000 dilution Lane 1: A431 whole cell lysate Lane 2: Ramos whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Predicted band size : 18 kDa Blocking/Dilution buffer: 5% NFDM/TBST. |
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Bik Antibody (BH3) (Cat. #P34497) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the Bik antibody detected the Bik protein (arrow). |
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Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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