库存-现货
瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to BIN1

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别名:AMPH2; AMPHL; SH3P9
应用:WB
反应种属:Human
规格:50μl/100μl

Description
This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in ten transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described.
Specification
Aliases AMPH2; AMPHL; SH3P9
Swissprot O00499
WB Predicted band size 65 kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Fusion protein of human BIN1
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Application
WB 1/200-1/1000
ELISA 1/1000-1/2000

Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Raji cells, Primary antibody: P00203(BIN1 Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds

本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。