Rabbit Polyclonal Antibody to BOD1

包装: 1G|100G|500G|1KG|100KG

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别名:FAM44B
应用:IHC
反应种属:Human, Mouse, Rat
规格：50μl/100μl

Description
Bod1, a protein conserved throughout metazoans that associates with a large macromolecular complex and localizes with kinetochores and spindle poles during mitosis. Bod1-depleted cells form syntelic attachments that can oscillate and generate enough force to separate sister kinetochores, suggesting that microtubule-kinetochore interactions were intact. Releasing Bod1-depleted cells from a monastrol block increases the frequency of syntelic attachments and the number of cells displaying biorientation defects.

Description

Bod1, a protein conserved throughout metazoans that associates with a large macromolecular complex and localizes with kinetochores and spindle poles during mitosis. Bod1-depleted cells form syntelic attachments that can oscillate and generate enough force to separate sister kinetochores, suggesting that microtubule-kinetochore interactions were intact. Releasing Bod1-depleted cells from a monastrol block increases the frequency of syntelic attachments and the number of cells displaying biorientation defects.

Specification
Aliases	FAM44B
Swissprot	Q96IK1
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse, Rat
Immunogen	Synthetic peptide of human BOD1
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
IHC	1/50-1/200
ELISA	1/1000-1/5000

	The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using P11604(BOD1 Antibody) at dilution 1/60. (Original magnification: ×200)
	The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P11604(BOD1 Antibody) at dilution 1/60. (Original magnification: ×200)