中文 
别名:CCAAT/enhancer-binding protein alpha C/EBP alpha CEBPA;应用:WB
反应种属:Human
规格：50μl/100μl
| Description |
|---|
| The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The encoded protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the encoded protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.Xanthopoulos K.G. Biochem. Biophys. Res. Commun. 215:106-113(1995)Schalwijk J. Biol. Chem. Hoppe-Seyler 378:373-379(1997)SeattleSNPs variation discovery resource Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases |
| Specification | |
|---|---|
| Aliases | CCAAT/enhancer-binding protein alpha C/EBP alpha CEBPA; |
| Entrez GeneID | 1050; |
| Swissprot | P49715 |
| WB Predicted band size | 42kDa |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Peptide sequence around phosphorylation site of threonine 230 (P-P-T(p)-P-V) derived from Human C/EBP-α. |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Application | |
|---|---|
| WB | 1/500-1/1000 |
 |
Western blot analysis of extracts from cos-7 cells (Lane 2), using C/EBP-α (Phospho-Thr230) Antibody P40488. The lane on the left is treated with antigen-specific peptide. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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