Rabbit Polyclonal Antibody to c-Jun (Ab-243)

包装: 1G|100G|500G|1KG|100KG

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别名:Activator protein 1; AH119; AP-1; AP1; c-Jun
应用:WB,IHC
反应种属:Human,Mouse,Rat
规格：50μl/100μl

Description
Transcription factor that recognizes and binds to the enhancer heptamer motif 5′-TGA[CG]TCA-3′. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.Boyle W J, et al. (1991) Cell. 64(3): 573-584.Binetruy B, et al. (1991) Nature. 351: 122-127.Smeal T, et al. (1991) Nature. 354:494-496.Derijard B, et al. (1994) Cell. 76:1025-1037.Kyriakis J M, et al. (1994) Nature. 369: 156-160.

Description

Transcription factor that recognizes and binds to the enhancer heptamer motif 5′-TGA[CG]TCA-3′. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.Boyle W J, et al. (1991) Cell. 64(3): 573-584.Binetruy B, et al. (1991) Nature. 351: 122-127.Smeal T, et al. (1991) Nature. 354:494-496.Derijard B, et al. (1994) Cell. 76:1025-1037.Kyriakis J M, et al. (1994) Nature. 369: 156-160.

Specification
Aliases	Activator protein 1; AH119; AP-1; AP1; c-Jun
Entrez GeneID	3725;
Swissprot	P05412
WB Predicted band size	43kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthesized non-phosphopeptide derived from human c-Jun around the phosphorylation site of serine 243.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Application
WB	1/500-1/3000
IHC	1/50-1/100

	Western blot analysis of extracts from HeLa cells, using c-Jun (Ab-243) antibody P41694.
	Immunohistochemistry analysis of paraffin-embedded human brain tissue, using c-Jun (Ab-243) antibody P41694.