Rabbit Polyclonal Antibody to c-Kit

包装: 1G|100G|500G|1KG|100KG

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别名:KIT; SCFR; Mast/stem cell growth factor receptor Kit; SCFR; Piebald trait protein; PBT; Proto-oncogene c-Kit; Tyrosine-protein kinase Kit; p145 c-kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD antigen CD117
应用:WB,IHC,ICC
反应种属:Human,Mouse,Rat,Monkey
规格：50μl/100μl

Description
KIT encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. KIT is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism.

Specification
Aliases	KIT; SCFR; Mast/stem cell growth factor receptor Kit; SCFR; Piebald trait protein; PBT; Proto-oncogene c-Kit; Tyrosine-protein kinase Kit; p145 c-kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD antigen CD117
Entrez GeneID	3815
Swissprot	P10721
WB Predicted band size	Calculated MW: 110 kDa; Observed MW: 120 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat,Monkey
Immunogen	The antiserum was produced against synthesized peptide derived from human c-Kit. AA range:688-737
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Application
WB	1/500-1/1000
IHC	1/50-1/100
ICC	1/50-1/200
ELISA	1/10000

	Western blot analysis of c-Kit in COS7/A549 lysates using c-Kit antibody.The lane on the right is blocked with the synthesized peptide.
	Immunohistochemistry analysis of paraffin-embedded Human Mammary cancer using c-Kit antibody.High-pressure and temperature Tris-EDTA pH 8.0 was used for antigen retrieval.
	Immunohistochemical analysis of paraffin-embedded Human tonsils using c-Kit antibody.High-pressure and temperature Tris-EDTA pH 8.0 was used for antigen retrieval.
	Immunohistochemistry analysis of paraffin-embedded Human Mammary cancer using c-Kit antibody. High-pressure and temperature Tris-EDTA pH 8.0 was used for antigen retrieval.