Rabbit Polyclonal Antibody to c-Src (phospho Tyr419)

包装: 1G|100G|500G|1KG|100KG

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别名:SRC; SRC1; Proto-oncogene tyrosine-protein kinase Src; Proto-oncogene c-Src; pp60c-src; p60-Src
应用:WB,IHC
反应种属:Human,Mouse,Rat
规格：50μl/100μl

Description
SRC proto-oncogene, non-receptor tyrosine kinase(SRC) Homo sapiens This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008],

Description

SRC proto-oncogene, non-receptor tyrosine kinase(SRC) Homo sapiens This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008],

Specification
Aliases	SRC; SRC1; Proto-oncogene tyrosine-protein kinase Src; Proto-oncogene c-Src; pp60c-src; p60-Src
Entrez GeneID	6714
Swissprot	P12931
WB Predicted band size	60kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	The antiserum was produced against synthesized peptide derived from human Src around the phosphorylation site of Tyr418. AA range:386-435
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.