中文 
别名:PEO; PEO1; SCA8; ATXN8; IOSCA; PEOA3; SANDO; TWINL; MTDPS7; PRLTS5应用:WB,IHC
反应种属:Human
规格：50μl/100μl
| Description |
|---|
| This gene encodes a hexameric DNA helicase which unwinds short stretches of double-stranded DNA in the 5′ to 3′ direction and, along with mitochondrial single-stranded DNA binding protein and mtDNA polymerase gamma, is thought to play a key role in mtDNA replication. The protein localizes to the mitochondrial matrix and mitochondrial nucleoids. Mutations in this gene cause infantile onset spinocerebellar ataxia (IOSCA) and progressive external ophthalmoplegia (PEO) and are also associated with several mitochondrial depletion syndromes. |
| Specification | |
|---|---|
| Aliases | PEO; PEO1; SCA8; ATXN8; IOSCA; PEOA3; SANDO; TWINL; MTDPS7; PRLTS5 |
| Entrez GeneID | 56652; |
| Swissprot | Q96RR1 |
| WB Predicted band size | 77kDa |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Fusion protein of human C10orf2 |
| Formulation | Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
| Application | |
|---|---|
| WB | 1/500-1/2000 |
| IHC | 1/25-1/100 |
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Gel: 8%SDS-PAGE Lysate: 40 μg Lane 1-3: K562, hela and Jurkat cell Primary antibody: 1/400 dilution Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 20 seconds |
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Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using P43414 at dilution 1/20. |
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Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue using P43414 at dilution 1/20. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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