Rabbit Polyclonal Antibody to C1QB

包装: 1G|100G|500G|1KG|100KG

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别名:complement C1q subcomponent B; complement component 1; q subcomponent; B;
应用:WB,ICC
反应种属:Human
规格：50μl/100μl

Description
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca2+-dependent C1r2C1s2 proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.Reid K.B.M.; Biochem. J. 231:729-735(1985).Gregory S.G., Nature 441:315-321(2006).The MGC Project Team; Genome Res. 14:2121-2127(2004).

Description

C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca2+-dependent C1r2C1s2 proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.Reid K.B.M.; Biochem. J. 231:729-735(1985).Gregory S.G., Nature 441:315-321(2006).The MGC Project Team; Genome Res. 14:2121-2127(2004).

Specification
Aliases	complement C1q subcomponent B; complement component 1; q subcomponent; B;
Entrez GeneID	713;
Swissprot	P02746
WB Predicted band size	28kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthesized peptide derived from internal of human C1QB.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Application
WB	1/500-1/3000
ICC	1/100-1/500

	Western blot analysis of extracts from Jurkat cells, using C1QB antibody P42368.
	Immunofluorescence analysis of A549 cells, using C1QB antibody P42368.