Rabbit Polyclonal Antibody to C1QC

包装: 1G|100G|500G|1KG|100KG

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别名:Complement C1q subcomponent subunit C;
应用:WB,IHC
反应种属:Human,Rat
规格：50μl/100μl

Description
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca2+-dependent C1r2C1s2 proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.Sellar G.C., Biochem. J. 274:481-490(1991).Dai F.Y., Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases.Ota T., Nat. Genet. 36:40-45(2004).

Description

C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca2+-dependent C1r2C1s2 proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.Sellar G.C., Biochem. J. 274:481-490(1991).Dai F.Y., Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases.Ota T., Nat. Genet. 36:40-45(2004).

Specification
Aliases	Complement C1q subcomponent subunit C;
Entrez GeneID	714;
Swissprot	P02747
WB Predicted band size	30kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Rat
Immunogen	Synthesized peptide derived from internal of human C1QC.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Application
WB	1/500-1/3000
IHC	1/50-1/100

	Western blot analysis of extracts from rat lung cells, using C1QC antibody P42369.
	Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using C1QC antibody P42369.