中文 
别名:Complement C2, C3/C5 convertase, Complement C2b fragment, Complement C2a fragment, C2应用:WB
反应种属:Human, Hamster
规格：50μl/100μl
| Description |
|---|
| Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined. |
| Specification | |
|---|---|
| Aliases | Complement C2, C3/C5 convertase, Complement C2b fragment, Complement C2a fragment, C2 |
| Entrez GeneID | 717 |
| Swissprot | P06681 |
| WB Predicted band size | 83.3kDa |
| Host/Isotype | Rabbit IgG |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Hamster |
| Immunogen | This C2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-176 amino acids from the N-terminal region of human C2. |
| Formulation | Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Application | |
|---|---|
| WB | 1/1000 |
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C2 Antibody (N-term) (Cat. #P30824) western blot analysis in CHO cell line lysates (35ug/lane).This demonstrates the C2 antibody detected the C2 protein (arrow). |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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