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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to Caldesmon (Phospho-Ser789)

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别名:CDM, HCAD, LCAD, H-CAD, L-CAD
应用:WB
反应种属:Human,Mouse,Rat
规格:50μl/100μl

Description
Actin- and myosin-binding protein implicated in the regulation of actomyosin interactions in smooth muscle and nonmuscle cells (could act as a bridge between myosin and actin filaments). Stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, inhibits the actomyosin ATPase by binding to F-actin. This inhibition is attenuated by calcium-calmodulin and is potentiated by tropomyosin. Interacts with actin, myosin, two molecules of tropomyosin and with calmodulin. Also play an essential role during cellular mitosis and receptor capping. Involved in Schwann cell migration during peripheral nerve regeneration
Specification
Aliases CDM, HCAD, LCAD, H-CAD, L-CAD
Entrez GeneID 800;
Swissprot Q05682
WB Predicted band size 80kDa
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen Peptide sequence around phosphorylation site of serine 789
(V-T-S(p)-P-T) derived from Human Caldesmon.
Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Application
WB 1/500-1/1000

Western blot analysis of extracts from Rat heart tissue using Caldesmon (Phospho-Ser789) Antibody P40641.The lane on the right is treated with the antigen-specific peptide.

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。