Rabbit Polyclonal Antibody to CAPNS1

包装: 1G|100G|500G|1KG|100KG

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别名:30K, CANP, CDPS, CSS1, CANPS, CAPN4, CALPAIN4
应用:WB,IHC
反应种属:Human, Mouse, Rat
规格：50μl/100μl

Description
Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. This gene encodes a small subunit common to both calpain I and II and is associated with myotonic dystrophy. Two transcript variants encoding the same protein have been identified for this gene.

Description

Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. This gene encodes a small subunit common to both calpain I and II and is associated with myotonic dystrophy. Two transcript variants encoding the same protein have been identified for this gene.

Specification
Aliases	30K, CANP, CDPS, CSS1, CANPS, CAPN4, CALPAIN4
Swissprot	P04632
WB Predicted band size	28 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse, Rat
Immunogen	Fusion protein of human CAPNS1
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
WB	1/500-1/2000
IHC	1/50-1/200
ELISA	1/1000-1/5000

	Gel: 12%SDS-PAGE, Lysate: 60 μg, Lane 1-2: K562 cells, NIH/3T3 cells, Primary antibody: P07142(CAPNS1 Antibody) at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 15 seconds
	The image is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using P07142(CAPNS1 Antibody) at dilution 1/60. (Original magnification: ×200)
	The image is immunohistochemistry of paraffin-embedded Human brain tissue using P07142(CAPNS1 Antibody) at dilution 1/60. (Original magnification: ×200)