Rabbit Polyclonal Antibody to CASC4 (C-term)

包装: 1G|100G|500G|1KG|100KG

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别名:Protein CASC4, Cancer susceptibility candidate gene 4 protein, CASC4
应用:WB,FCM
反应种属:Human, Mouse
规格：50μl/100μl

Description
The increased expression level of this gene is associated with HER-2/neu proto-oncogene overexpression. Amplification and resulting overexpression of this proto-oncogene are found in approximately 30% of human breast and 20% of human ovarian cancers. Further characterization of the product of this gene may yield insight into the fundamental biology and pathogenetic effects of HER-2/neu overexpression in human breast and ovarian cancer cells. Alternatively spliced variants encoding different isoforms have been identified for this gene.

Description

The increased expression level of this gene is associated
with HER-2/neu proto-oncogene overexpression. Amplification and
resulting overexpression of this proto-oncogene are found in
approximately 30% of human breast and 20% of human ovarian cancers.
Further characterization of the product of this gene may yield
insight into the fundamental biology and pathogenetic effects of
HER-2/neu overexpression in human breast and ovarian cancer cells.
Alternatively spliced variants encoding different isoforms have
been identified for this gene.

Specification
Aliases	Protein CASC4, Cancer susceptibility candidate gene 4 protein, CASC4
Entrez GeneID	113201
Swissprot	Q6P4E1
WB Predicted band size	49.5kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse
Immunogen	This CASC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 336-365 amino acids from the C-terminal region of human CASC4.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/1000
FCM	1/10-1/50

	CASC4 Antibody (C-term) (Cat. #P30799) western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstrates the CASC4 antibody detected the CASC4 protein (arrow).
	CASC4 Antibody (C-term) (Cat. #P30799) flow cytometric analysis of Neuro-2a cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.