别名:MCH6; APAF3; APAF-3; PPP1R56; ICE-LAP6应用:WB
反应种属:Human,Mouse
规格:50μl/100μl
Description |
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This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspase APAF1; this step is thought to be one of the earliest in the caspase activation cascade. Alternative splicing results in two transcript variants which encode different isoforms. |
Specification | |
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Aliases | MCH6; APAF3; APAF-3; PPP1R56; ICE-LAP6 |
Entrez GeneID | 842; |
Swissprot | P55211 |
WB Predicted band size | 46kDa |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse |
Immunogen | Fusion protein corresponding to a region derived from internal residues of human Caspase-9 |
Formulation | Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
Application | |
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WB | 1/500-1/1000 |
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Gel: 8%SDS-PAGE Lysates (from left to right): HepG2 and Hela cell Amount of lysate: 20ug per lane Primary antibody: 1/500 dilution Secondary antibody dilution: 1/8000 Exposure time: 1 minute |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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