Rabbit Polyclonal Antibody to CASP9 (active)

包装: 1G|100G|500G|1KG|100KG

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别名:MCH6; APAF3; APAF-3; PPP1R56; ICE-LAP6; CASPASE-9c
应用:IHC
反应种属:Human, Mouse
规格：50μl/100μl

Description
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspase APAF1; this step is thought to be one of the earliest in the caspase activation cascade. Alternative splicing results in two transcript variants which encode different isoforms.

Description

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspase APAF1; this step is thought to be one of the earliest in the caspase activation cascade. Alternative splicing results in two transcript variants which encode different isoforms.

Specification
Aliases	MCH6; APAF3; APAF-3; PPP1R56; ICE-LAP6; CASPASE-9c
Swissprot	P55211
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse
Immunogen	Synthetic peptide of human CASP9 (active)
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
IHC	1/100-1/300
ELISA	1/2000-1/10000

	The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using P04531(CASP9 (active) Antibody) at dilution 1/80. (Original magnification: ×200)
	The image is immunohistochemistry of paraffin-embedded Human lung cancer tissue using P04531(CASP9 (active) Antibody) at dilution 1/80. (Original magnification: ×200)