中文 
别名:CAR; FHH; FIH; HHC; EIG8; HHC1; NSHPT; PCAR1; GPRC2A; HYPOC1应用:WB,IHC
反应种属:Human
规格：50μl/100μl
| Description |
|---|
| The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism. |
| Specification | |
|---|---|
| Aliases | CAR; FHH; FIH; HHC; EIG8; HHC1; NSHPT; PCAR1; GPRC2A; HYPOC1 |
| Entrez GeneID | 846; |
| Swissprot | P41180 |
| WB Predicted band size | 121kDa |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthetic protein corresponding to residues near the C terminal of human CASR |
| Formulation | Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
| Application | |
|---|---|
| WB | 1/200-1/1000 |
| IHC | 1/ 50-300 |
 |
Gel: 6%SDS-PAGE lysate: 40ug, Lane: Hela cell lysate,Primary antibody: 46408(CASR Antibody) at dilution 1/450 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes |
 |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 46408(CASR Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: x200) |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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