中文 
别名:CGL3; PPH3; BSCL3; VIP21; MSTP085应用:WB
反应种属:Human, Mouse, Rat
规格：50μl/100μl
| Description |
|---|
| The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1. |
| Specification | |
|---|---|
| Aliases | CGL3; PPH3; BSCL3; VIP21; MSTP085 |
| Swissprot | Q03135 |
| WB Predicted band size | 20 kDa |
| Host/Isotype | Rabbit IgG |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | Synthetic peptide of human CAV1 |
| Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Application | |
|---|---|
| WB | 1/500-1/2000 |
| ELISA | 1/2000-1/5000 |
 |
Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Human leiomyosarcoma tissue, Primary antibody: P11547(CAV1 Antibody) at dilution 1/525, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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