Rabbit Polyclonal Antibody to CBCP6

包装: 1G|100G|500G|1KG|100KG

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别名:ATP/GTP-binding protein-like 4; CBPC6; CCP6; cytosolic carboxypeptidase 6; EC 3.4.17.-
应用:WB
反应种属:Human
规格：50μl/100μl

Description
Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5 By similarity.Ota T., Nat. Genet. 36:40-45(2004).Gregory S.G., Nature 441:315-321(2006).

Description

Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5 By similarity.Ota T., Nat. Genet. 36:40-45(2004).Gregory S.G., Nature 441:315-321(2006).

Specification
Aliases	ATP/GTP-binding protein-like 4; CBPC6; CCP6; cytosolic carboxypeptidase 6; EC 3.4.17.-
Entrez GeneID	84871;
Swissprot	Q5VU57
WB Predicted band size	62kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthesized peptide derived from internal of human CBCP6.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.