中文 
别名:C-C CKR-5; CKR5; CHEMR13; CMKBR5; CCR-5应用:WB
反应种属:Human
规格：50μl/100μl
| Description |
|---|
| Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates.Martin Oppermann, J. Biol. Chem., Mar 1999; 274: 8875Beatrix Pollok-Kopp, J. Biol. Chem., Jan 2003; 278: 2190 – 2198Ramtin Rahbar, J. Virol., Jul 2006; 80: 7245 – 7259H Olbrich, J. Leukoc. Biol., Mar 1999; 65: 281 |
| Specification | |
|---|---|
| Aliases | C-C CKR-5; CKR5; CHEMR13; CMKBR5; CCR-5 |
| Entrez GeneID | 1234; |
| Swissprot | P51681 |
| WB Predicted band size | 40kDa |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Peptide sequence around phosphorylation site of Serine 349 (E-I-S(p)-V-G) derived from Human CCR5. |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Application | |
|---|---|
| WB | 1/500-1/1000 |
 |
Western blot analysis of extracts from A549 cells (Lane 2), using CCR5 (Phospho-Ser349) Antibody P40372. The lane on the left is treated with antigen-specific peptide. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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