Rabbit Polyclonal Antibody to CCR8

包装: 1G|100G|500G|1KG|100KG

现货支持定制

QQ咨询
| 微信咨询

满200元免运费
正品保障提供发票
现货闪电当时发货

别名:C-C chemokine receptor type 8, C-C CKR-8, CC-CKR-8, CCR-8, CC chemokine receptor CHEMR1, CMKBRL2, Chemokine receptor-like 1, CKR-L1, GPR-CY6, GPRCY6, TER1, CDw198, CCR8, CKRL1, CMKBR8, CMKBRL2
应用:WB,FCM
反应种属:Human, Mouse, Rat
规格：50μl/100μl

Description
CCR8 encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. CCR8 is located at the chemokine receptor gene cluster region.

Description

CCR8 encodes a member of the beta chemokine receptor
family, which is predicted to be a seven transmembrane protein
similar to G protein-coupled receptors. Chemokines and their
receptors are important for the migration of various cell types
into the inflammatory sites. This receptor protein preferentially
expresses in the thymus. I-309, thymus activation-regulated
cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1
beta) have been identified as ligands of this receptor. Studies of
this receptor and its ligands suggested its role in regulation of
monocyte chemotaxis and thymic cell apoptosis. More specifically,
this receptor may contribute to the proper positioning of activated
T cells within the antigenic challenge sites and specialized areas
of lymphoid tissues. CCR8 is located at the chemokine receptor
gene cluster region.

Specification
Aliases	C-C chemokine receptor type 8, C-C CKR-8, CC-CKR-8, CCR-8, CC chemokine receptor CHEMR1, CMKBRL2, Chemokine receptor-like 1, CKR-L1, GPR-CY6, GPRCY6, TER1, CDw198, CCR8, CKRL1, CMKBR8, CMKBRL2
Entrez GeneID	1237
Swissprot	P51685
WB Predicted band size	40.8kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse, Rat
Immunogen	This CCR8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 305-335 amino acids of human CCR8.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/1000
FCM	1/10-1/50

	CCR8 Antibody (C-term) (Cat. #P30793) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the CCR8 antibody detected the CCR8 protein (arrow).
	CCR8 Antibody (C-term) (Cat. #P30793) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.