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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to CD1B (N-term)

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别名:T-cell surface glycoprotein CD1b, CD1b, CD1B
应用:WB
反应种属:Human
规格:50μl/100μl

Description
This gene encodes a member of the CD1 family of
transmembrane glycoproteins, which are structurally related to the
major histocompatibility complex (MHC) proteins and form
heterodimers with beta-2-microglobulin. The CD1 proteins mediate
the presentation of primarily lipid and glycolipid antigens of self
or microbial origin to T cells. The human genome contains five CD1
family genes organized in a cluster on chromosome 1. The CD1 family
members are thought to differ in their cellular localization and
specificity for particular lipid ligands. The protein encoded by
this gene localizes to late endosomes and lysosomes via a
tyrosine-based motif in the cytoplasmic tail, and requires
vesicular acidification to bind lipid antigens. [provided by
RefSeq].
Specification
Aliases T-cell surface glycoprotein CD1b, CD1b, CD1B
Entrez GeneID 910
Swissprot P29016
WB Predicted band size 36.9kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen This CD1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 57-85 amino acids from the N-terminal region of human CD1B.
Formulation Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Application
WB 1/1000

Western blot analysis of CD1B (arrow) using rabbit polyclonal CD1B Antibody (N-term) (Cat. #P31996). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CD1B gene.

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。