Rabbit Polyclonal Antibody to CD253

包装: 1G|100G|500G|1KG|100KG

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别名:Tumor necrosis factor ligand superfamily member 10; TNF-related apoptosis-inducing ligand; Protein TRAIL; Apo-2 ligand; Apo-2L
应用:WB,ICC
反应种属:Human
规格：50μl/100μl

Description
Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis.Wiley S.R., Immunity 3:673-682(1995).Pitti R.M., J. Biol. Chem. 271:12687-12690(1996).Hymowitz S.G., Mol. Cell 4:563-571(1999).

Description

Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis.Wiley S.R., Immunity 3:673-682(1995).Pitti R.M., J. Biol. Chem. 271:12687-12690(1996).Hymowitz S.G., Mol. Cell 4:563-571(1999).

Specification
Aliases	Tumor necrosis factor ligand superfamily member 10; TNF-related apoptosis-inducing ligand; Protein TRAIL; Apo-2 ligand; Apo-2L
Entrez GeneID	8743;
Swissprot	P50591
WB Predicted band size	30kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthesized peptide derived from internal of human CD253.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Application
WB	1/500-1/3000
ICC	1/100-1/500

	Western blot analysis of extracts from 293 cells and HUVEC cells, using CD253 antibody P41956.
	Immunofluorescence analysis of A549 cells, using CD253 antibody P41956.