Rabbit Polyclonal Antibody to CD3 epsilon

包装: 1G|100G|500G|1KG|100KG

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别名:CD3E; T3E; T-cell surface glycoprotein CD3 epsilon chain; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e
应用:WB,IHC,FCM,IP
反应种属:Human
规格：50μl/100μl

Description
The CD3 complex mediates signal transduction. When T cells encounter antigens via the T cell receptor (TCR), information about the quantity and quality of antigens is relayed to the intracellular signal transduction machinery . This activation process depends mainly on CD3 (Cluster of Differentiation 3), a multiunit protein complex that directly associates with the TCR. CD3 is composed of four polypeptides: ζ, γ, ε and δ.

Description

The CD3 complex mediates signal transduction. When T cells encounter antigens via the T cell receptor (TCR), information about the quantity and quality of antigens is relayed to the intracellular signal transduction machinery . This activation process depends mainly on CD3 (Cluster of Differentiation 3), a multiunit protein complex that directly associates with the TCR. CD3 is composed of four polypeptides: ζ, γ, ε and δ.

Specification
Aliases	CD3E; T3E; T-cell surface glycoprotein CD3 epsilon chain; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e
Entrez GeneID	916
Swissprot	P07766
WB Predicted band size	Calculated MW: 23 kDa; Observed MW: 23 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	A synthesized peptide derived from human CD3 epsilon
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Application
IP	1/20
WB	1/500-1/1000
IHC	1/50-1/100
FCM	1/50-1/100

	Western blot analysis of CD3 epsilon in Jurkat lysates using CD3 epsilon antibody.
	Immunohistochemistry analysis of paraffin-embedded Human colon cancer using CD3 epsilon antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.