Rabbit Polyclonal Antibody to CD31

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别名:Platelet endothelial cell adhesion molecule; PECAM-1; EndoCAM; GPIIA’; PECA1; CD antigen CD31
应用:WB,IHC,ICC
反应种属:Human,Mouse
规格：50μl/100μl

Description
PECAM-1 a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions. Plays a role in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, cell migration, negative regulation of immune cell signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. Undergoes alternative splicing, generating multiple isoforms in vascular beds of various tissues.

Description

PECAM-1 a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions. Plays a role in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, cell migration, negative regulation of immune cell signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. Undergoes alternative splicing, generating multiple isoforms in vascular beds of various tissues.

Specification
Aliases	Platelet endothelial cell adhesion molecule; PECAM-1; EndoCAM; GPIIA’; PECA1; CD antigen CD31
Entrez GeneID	5175
Swissprot	P16284
WB Predicted band size	Calculated MW: 83 kDa; Observed MW: 83 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	synthesized peptide of human PECAM-1. AA range:686-735
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Application
WB	1/500-1/1000
IHC	1/50-1/100
ICC	1/50-1/200
ELISA	1/10000

	Western blot analysis of CD31 in HepG2, K562, L929, mouse brain lysates using CD31 antibody.
	Immunofluorescence analysis of CD31 in HeLa using CD31 antibody. The picture on the right is blocked using synthesized peptide.
	Immunohistochemistry analysis of paraffin-embedded CD31 in paraffin-embedded Human kidney using CD31 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.