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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to CD320

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别名:CD320 antigen, 8D6 antigen, FDC-signaling molecule 8D6, FDC-SM-8D6, Transcobalamin receptor, TCblR, CD320, CD320, 8D6A
应用:WB
反应种属:Human
规格:50μl/100μl

Description
The CD320 antigen gene encodes the transcobalamin receptor
(TCBLR). Cellular uptake of cobalamin (vitamin B12) is mediated by
receptors expressed on the cell surface. Transcobalamin II (TCN2;
MIM 613441), a plasma protein secreted by endothelial cells, binds
the cobalamin absorbed in the distal ileum and carries 10 to 30% of
total circulating cobalamin. CD320 encodes a transcobalamin
receptor that binds TCN2-cobalamin at the plasma membrane and
internalizes the complex by endocytosis (Quadros et al., 2009
[PubMed 18779389]).
Specification
Aliases CD320 antigen, 8D6 antigen, FDC-signaling molecule 8D6, FDC-SM-8D6, Transcobalamin receptor, TCblR, CD320, CD320, 8D6A
Entrez GeneID 51293
Swissprot Q9NPF0
WB Predicted band size 29.0kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen This CD320 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 153-182 amino acids from the C-terminal region of human CD320.
Formulation Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Application
WB 1/1000

CD320 Antibody (C-term) (Cat. #P31222) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the CD320 antibody detected the CD320 protein (arrow).

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。