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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to CD4

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别名:B-cell surface antigen CD40; Bp50; CD40 antigen; CD40L receptor; CDw40
应用:WB,IHC
反应种属:Human
规格:50μl/100μl

Description
Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion.Carlos Reyes-Moreno, J. Biol. Chem., May 2007; 10.1074.Hongwei Qin, Blood, Nov 2005; 106: 3114 – 3122. Meera J. Nathan, J. Immunol., Jun 2004; 172: 6626 – 6633. Clare C. Davies, Mol. Cell. Biol., Nov 2005; 25: 9806 – 9819.
Specification
Aliases B-cell surface antigen CD40; Bp50; CD40 antigen; CD40L receptor; CDw40
Entrez GeneID 958;
Swissprot P25942
WB Predicted band size 30kDa
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Synthesized peptide derived from C-terminal of human CD40.
Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Application
WB 1/500-1/3000
IHC 1/50-1/100

Western blot analysis of extracts from COS7 cells, using CD40 antibody P41838.
Western blot analysis of extracts from JK cells (Lane 2), K562 cells (Lane 3) and 293 cells (Lane 4), using CD40 antiobdy P41838. The lane on the left is treated with synthesized peptide.
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using CD40 antibody P41838.

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。