别名:B-cell surface antigen CD40; Bp50; CD40 antigen; CD40L receptor; CDw40应用:WB,IHC
反应种属:Human
规格:50μl/100μl
Description |
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Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion.Carlos Reyes-Moreno, J. Biol. Chem., May 2007; 10.1074.Hongwei Qin, Blood, Nov 2005; 106: 3114 – 3122. Meera J. Nathan, J. Immunol., Jun 2004; 172: 6626 – 6633. Clare C. Davies, Mol. Cell. Biol., Nov 2005; 25: 9806 – 9819. |
Specification | |
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Aliases | B-cell surface antigen CD40; Bp50; CD40 antigen; CD40L receptor; CDw40 |
Entrez GeneID | 958; |
Swissprot | P25942 |
WB Predicted band size | 30kDa |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Synthesized peptide derived from C-terminal of human CD40. |
Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Application | |
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WB | 1/500-1/3000 |
IHC | 1/50-1/100 |
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Western blot analysis of extracts from COS7 cells, using CD40 antibody P41838. |
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Western blot analysis of extracts from JK cells (Lane 2), K562 cells (Lane 3) and 293 cells (Lane 4), using CD40 antiobdy P41838. The lane on the left is treated with synthesized peptide. |
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Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using CD40 antibody P41838. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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