别名:G6VTS76519应用:IHC
反应种属:Human
规格:50μl/100μl
Description |
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WD-repeats are motifs that are found in a variety of proteins and are characterized by a conserved core of 40-60 amino acids that commonly form a tertiary propeller structure. While proteins that contain WD-repeats participate in a wide range of cellular functions, they are generally involved in regulatory mechanisms concerning chromatin assembly, cell cycle control, signal transduction, RNA processing, apoptosis and vesicular trafficking. Cdc20B (cell division cycle 20 homolog B) is a 519 amino acid protein that contains seven WD repeats and is thought to play a role in cell cycle control. Multiple isoforms of Cdc20B exist due to alternative splicing events. The gene encoding Cdc20B maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome. |
Specification | |
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Aliases | G6VTS76519 |
Swissprot | Q86Y33 |
Host/Isotype | Rabbit IgG |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Synthetic peptide of human CDC20B |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Application | |
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IHC | 1/30-1/150 |
ELISA | 1/5000-1/10000 |
The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P06160(CDC20B Antibody) at dilution 1/30. (Original magnification: ×200) |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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