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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to CDC25A (Ab-178)

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别名:CDC25M3; Dual specificity phosphatase Cdc25A; EC 3.1.3.48; M-phase inducer phosphatase 1; MPIP1
应用:WB
反应种属:Human
规格:50μl/100μl

Description
Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDK1 and stimulates its kinase activity. Also dephosphorylates CDK2 in complex with cyclin E, in vitro.Galaktionov K.I.,Cell 67:1181-1194(1991).The MGC Project Team;Genome Res. 14:2121-2127(2004).Wegener S., Eur. J. Cell Biol. 79:810-815(2000).
Specification
Aliases CDC25M3; Dual specificity phosphatase Cdc25A; EC 3.1.3.48; M-phase inducer phosphatase 1; MPIP1
Entrez GeneID 993;
Swissprot P30304
WB Predicted band size 49kDa
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Synthesized non-phosphopeptide derived from human CDC25A around the phosphorylation site of serine 178 (Q-N-S(p)-A-P).
Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Application
WB 1/500-1/3000

Western blot analysis of extracts from Jurkat cells, using CDC25A (Ab-178) antibody P41697.
Western blot analysis of extracts from HeLa cells (Lane 2) and 293 cells (Lane 3), using CDC25A (Ab-178) antiobdy P41697. The lane on the left is treated with synthesized peptide.

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。