别名:CDC25M3; Dual specificity phosphatase Cdc25A; EC 3.1.3.48; M-phase inducer phosphatase 1; MPIP1应用:WB
反应种属:Human
规格:50μl/100μl
Description |
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Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDK1 and stimulates its kinase activity. Also dephosphorylates CDK2 in complex with cyclin E, in vitro.Galaktionov K.I.,Cell 67:1181-1194(1991).The MGC Project Team;Genome Res. 14:2121-2127(2004).Wegener S., Eur. J. Cell Biol. 79:810-815(2000). |
Specification | |
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Aliases | CDC25M3; Dual specificity phosphatase Cdc25A; EC 3.1.3.48; M-phase inducer phosphatase 1; MPIP1 |
Entrez GeneID | 993; |
Swissprot | P30304 |
WB Predicted band size | 49kDa |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Synthesized non-phosphopeptide derived from human CDC25A around the phosphorylation site of serine 178 (Q-N-S(p)-A-P). |
Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Application | |
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WB | 1/500-1/3000 |
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Western blot analysis of extracts from Jurkat cells, using CDC25A (Ab-178) antibody P41697. |
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Western blot analysis of extracts from HeLa cells (Lane 2) and 293 cells (Lane 3), using CDC25A (Ab-178) antiobdy P41697. The lane on the left is treated with synthesized peptide. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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