Rabbit Polyclonal Antibody to CDCA2

包装: 1G|100G|500G|1KG|100KG

现货支持定制

QQ咨询
| 微信咨询

400-880-2824

满200元免运费
正品保障提供发票
现货闪电当时发货

别名:FLJ25804; MGC129906; MGC129907; cell division cycle associated 2;
应用:WB
反应种属:Human
规格：50μl/100μl

Description
Regulator of chromosome structure during mitosis required for condensin-depleted chromosomes to retain their compact architecture through anaphase. Acts by mediating the recruitment of phopsphatase PP1-gamma subunit (PPP1CC) to chromatin at anaphase and into the following interphase. At anaphase onset, its association with chromatin targets a pool of PPP1CC to dephosphorylate substrates.Walker M.G., Curr. Cancer Drug Targets 1:73-83(2001).Ota T., . Genet. 36:40-45(2004).Olsen J.V., Cell 127:635-648(2006).

Description

Regulator of chromosome structure during mitosis required for condensin-depleted chromosomes to retain their compact architecture through anaphase. Acts by mediating the recruitment of phopsphatase PP1-gamma subunit (PPP1CC) to chromatin at anaphase and into the following interphase. At anaphase onset, its association with chromatin targets a pool of PPP1CC to dephosphorylate substrates.Walker M.G., Curr. Cancer Drug Targets 1:73-83(2001).Ota T., . Genet. 36:40-45(2004).Olsen J.V., Cell 127:635-648(2006).

Specification
Aliases	FLJ25804; MGC129906; MGC129907; cell division cycle associated 2;
Entrez GeneID	157313;
Swissprot	Q69YH5
WB Predicted band size	113kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthesized peptide derived from C-terminal of human CDCA2.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.