Rabbit Polyclonal Antibody to CDH2

包装: 1G|100G|500G|1KG|100KG

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别名:Cadherin-2, CDw325, Neural cadherin, N-cadherin, CD325, CDH2, CDHN, NCAD
应用:WB,FCM
反应种属:Human
规格：50μl/100μl

Description
CDH2 is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product.

Description

CDH2 is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product.

Specification
Aliases	Cadherin-2, CDw325, Neural cadherin, N-cadherin, CD325, CDH2, CDHN, NCAD
Entrez GeneID	1000
Swissprot	P19022
WB Predicted band size	99.8kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	This CDH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 744-772 amino acids from the C-terminal region of human CDH2.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. Then the antibody is purified by peptide affinity purification.

Application
WB	1/1000
FCM	1/10-1/50

	Western blot analysis of CDH2 Antibody (C-term) (Cat.#P30223) in 293 cell line lysates (35ug/lane). CDH2(arrow) was detected using the purified Pab.
	Western blot analysis of CDH2 (arrow) using rabbit polyclonal CDH2 Antibody (C-term) (Cat.#P30223).293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CDH2 gene (Lane 2) (Origene Technologies).
	Flow cytometric analysis of 293 cells using CDH2 Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.