别名:7B4; CD144应用:IHC
反应种属:Human
规格:50μl/100μl
Description |
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This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but its full length sequence has not been determined. |
Specification | |
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Aliases | 7B4; CD144 |
Entrez GeneID | 1003; |
Swissprot | P33151 |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Synthetic peptide corresponding to residues near the C terminal of human cadherin 5, type 2 (vascular endothelium) |
Formulation | Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
Application | |
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IHC | 1/50-1/200 |
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Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using P42889 at dilution 1/50. |
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Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue using P42889 at dilution 1/50. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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