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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to CDK8

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别名:K35
应用:IHC
反应种属:Human, Mouse
规格:50μl/100μl

Description
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit cyclin C are components of the RNA polymerase II holoenzyme complex, which phosphorylates the carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II. This kinase has also been shown to regulate transcription by targeting the CDK7/cyclin H subunits of the general transcription initiation factor IIH (TFIIH), thus providing a link between the ‘Mediator-like’ protein complexes and the basal transcription machinery. 
Specification
Aliases K35
Swissprot P49336
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse
Immunogen Synthetic peptide of human CDK8
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Application
IHC 1/25-1/100
ELISA 1/2000-1/5000

The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P05601(CDK8 Antibody) at dilution 1/20. (Original magnification: ×200)

本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。