中文 
别名:Cyclin-dependent kinase-like 5, Serine/threonine-protein kinase 9, CDKL5, STK9应用:WB,IHC
反应种属:Human, Mouse
规格：50μl/100μl
| Description |
|---|
| Defects in STK9, a dual-specificity serine/threonine kinase, are a cause of atypical Rett syndrome. Rett syndrome is an X-linked dominant disease. It is a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females. Patients appear to develop normally until 6 to 18 months of age, then gradually lose speech and purposeful hand movements and develop microcephaly, seizures, autism, ataxia, intermittent hyperventilation, and stereotypic hand movements. After initial regression, the condition stabilizes and patients usually survive into adulthood. Rett syndrome due to CDKL5-associated mutations is characterized by a severe early-onset phenotype and atypical features such as infantile spasms. |
| Specification | |
|---|---|
| Aliases | Cyclin-dependent kinase-like 5, Serine/threonine-protein kinase 9, CDKL5, STK9 |
| Entrez GeneID | 6792 |
| Swissprot | O76039 |
| WB Predicted band size | 107.5kDa |
| Host/Isotype | Rabbit IgG |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | This CDKL5 (STK9) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 982-1012 amino acids from the C-terminal region of human CDKL5 (STK9). |
| Formulation | Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Application | |
|---|---|
| WB | 1/1000 |
| IHC | 1/100-1/500 |
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Anti-STK9 Antibody (F997) at 1:1000 dilution + Hela whole cell lysate
Lysates/proteins at 20 µg per lane. Secondary Predicted band size : 116 kDa Blocking/Dilution buffer: 5% NFDM/TBST. |
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The anti-STK9 Pab (Cat. #P33657) is used in Western blot to detect STK9 in mouse lung tissue lysate. |
 |
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with STK9 Antibody (C-term)(Cat.#P33657), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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