别名:Centrosomal protein of 164 kDa, Cep164, CEP164, KIAA1052, NPHP15应用:WB,FCM
反应种属:Human
规格:50μl/100μl
Description |
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Plays a role in microtubule organization and/or maintenance for the formation of primary cilia (PC), a microtubule-based structure that protrudes from the surface of epithelial cells. Plays a critical role in G2/M checkpoint and nuclear divisions. A key player in the DNA damage-activated ATR/ATM signaling cascade since it is required for the proper phosphorylation of H2AX, RPA,CHK2 and CHK1. Plays a critical role in chromosome segregation, acting as a mediator required for the maintenance of genomic stability through modulation of MDC1, RPA and CHK1. |
Specification | |
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Aliases | Centrosomal protein of 164 kDa, Cep164, CEP164, KIAA1052, NPHP15 |
Entrez GeneID | 22897 |
Swissprot | Q9UPV0 |
WB Predicted band size | 164.3kDa |
Host/Isotype | Rabbit IgG |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | This CE164 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 246-274 amino acids from the N-terminal region of human CE164. |
Formulation | Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Application | |
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WB | 1/1000 |
FCM | 1/10-1/50 |
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All lanes : Anti-CE164 Antibody (N-term) at 1:1000 dilution Lane 1: SH-SY5Y whole cell lysate Lane 2: A549 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Predicted band size : 164 kDa Blocking/Dilution buffer: 5% NFDM/TBST. |
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CE164 Antibody (N-term) (Cat. #P34248) flow cytometric analysis of A549 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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