库存-现货
瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to CEACAM1

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别名:BGP; BGP1; BGPI
应用:WB
反应种属:Human
规格:50μl/100μl

Description
This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of all variants has not been defined.
Specification
Aliases BGP; BGP1; BGPI
Swissprot P13688
WB Predicted band size 58 kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Synthetic peptide of human CEACAM1
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Application
WB 1/500-1/2000
ELISA 1/5000-1/10000

Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: A549 cell lysate, Primary antibody: P13929(CEACAM1 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 1 minute

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。