Rabbit Polyclonal Antibody to CEBPB

包装: 1G|100G|500G|1KG|100KG

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别名:AGP/EBP; C/EBP beta; C/EBP-related protein 2; CCAAT/enhancer binding protein beta; CEBPB
应用:WB
反应种属:Human,Mouse
规格：50μl/100μl

Description
Important transcription factor regulating the expression of genes involved in immune and inflammatory responses. Binds to regulatory regions of several acute-phase and cytokines genes and probably plays a role in the regulation of acute-phase reaction, inflammation and hemopoiesis. The consensus recognition site is 5′-T[TG]NNGNAA[TG]-3′. Plays an important role in adipose tissue differentiation. Regulates the transcriptional induction of peroxisome proliferator-activated receptor gamma (PPARG) as well as other adipogenesis key player genes. Isoform 3:acts as a dominant negative through heterodimerization with isoform 2.Akira S., EMBO J. 9:1897-1906(1990).Wan D., Proc. Natl. Acad. Sci. U.S.A. 101:15724-15729(2004).Deloukas P., Nature 414:865-871(2001).

Description

Important transcription factor regulating the expression of genes involved in immune and inflammatory responses. Binds to regulatory regions of several acute-phase and cytokines genes and probably plays a role in the regulation of acute-phase reaction, inflammation and hemopoiesis. The consensus recognition site is 5′-T[TG]NNGNAA[TG]-3′. Plays an important role in adipose tissue differentiation. Regulates the transcriptional induction of peroxisome proliferator-activated receptor gamma (PPARG) as well as other adipogenesis key player genes. Isoform 3:acts as a dominant negative through heterodimerization with isoform 2.Akira S., EMBO J. 9:1897-1906(1990).Wan D., Proc. Natl. Acad. Sci. U.S.A. 101:15724-15729(2004).Deloukas P., Nature 414:865-871(2001).

Specification
Aliases	AGP/EBP; C/EBP beta; C/EBP-related protein 2; CCAAT/enhancer binding protein beta; CEBPB
Entrez GeneID	1051;
Swissprot	P17676
WB Predicted band size	49kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	Synthesized peptide derived from internal of human CEBPB.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.