Rabbit Polyclonal Antibody to CENP-A (phospho Ser7)

包装: 1G|100G|500G|1KG|100KG

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别名:CENPA; Histone H3-like centromeric protein A; Centromere autoantigen A; Centromere protein A; CENP-A
应用:ICC
反应种属:Human
规格：50μl/100μl

Description
centromere protein A(CENPA) Homo sapiens Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. This gene encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. Centromere protein A is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. The protein is a replication-independent histone that is a member of the histone H3 family. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Nov 2015],

Description

centromere protein A(CENPA) Homo sapiens Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. This gene encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. Centromere protein A is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. The protein is a replication-independent histone that is a member of the histone H3 family. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Nov 2015],

Specification
Aliases	CENPA; Histone H3-like centromeric protein A; Centromere autoantigen A; Centromere protein A; CENP-A
Entrez GeneID	1058
Swissprot	P49450
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	The antiserum was produced against synthesized peptide derived from human Centromeric Protein A around the phosphorylation site of Ser7. AA range:1-50
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.