库存-现货
瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to CEP104

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别名:GlyBP; ROC22; JBTS25; CFAP256; KIAA0562
应用:IHC
反应种属:Human
规格:50μl/100μl

Description
This gene encodes a centrosomal protein required for ciliogenesis and for ciliary tip structural integrity. The mammalian protein contains three amino-terminal hydrophobic domains, two glycosylation sites, four cysteine-rich motifs, and two regions with homology to the glutamate receptor ionotropic, NMDA 1 protein. During ciliogenesis, the encoded protein translocates from the distal tips of the centrioles to the tip of the elongating cilium. Knockdown of the protein in human retinal pigment cells results in severe defects in ciliogenesis with structural deformities at the ciliary tips. Allelic variants of this gene are associated with the autosomal-recessive disorder Joubert syndrome, which is characterized by a distinctive mid-hindbrain and cerebellar malformation, oculomotor apraxia, irregular breathing, developmental delay, and ataxia.
Specification
Aliases GlyBP; ROC22; JBTS25; CFAP256; KIAA0562
Swissprot O60308
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Synthetic peptide of human CEP104
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Application
IHC 1/25-1/100
ELISA 1/5000-1/10000

The image is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using P06180(CEP104 Antibody) at dilution 1/25. (Original magnification: ×200)
The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P06180(CEP104 Antibody) at dilution 1/25. (Original magnification: ×200)

本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。