别名:GlyBP; ROC22; JBTS25; CFAP256; KIAA0562应用:IHC
反应种属:Human
规格:50μl/100μl
Description |
---|
This gene encodes a centrosomal protein required for ciliogenesis and for ciliary tip structural integrity. The mammalian protein contains three amino-terminal hydrophobic domains, two glycosylation sites, four cysteine-rich motifs, and two regions with homology to the glutamate receptor ionotropic, NMDA 1 protein. During ciliogenesis, the encoded protein translocates from the distal tips of the centrioles to the tip of the elongating cilium. Knockdown of the protein in human retinal pigment cells results in severe defects in ciliogenesis with structural deformities at the ciliary tips. Allelic variants of this gene are associated with the autosomal-recessive disorder Joubert syndrome, which is characterized by a distinctive mid-hindbrain and cerebellar malformation, oculomotor apraxia, irregular breathing, developmental delay, and ataxia. |
Specification | |
---|---|
Aliases | GlyBP; ROC22; JBTS25; CFAP256; KIAA0562 |
Swissprot | O60308 |
Host/Isotype | Rabbit IgG |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Synthetic peptide of human CEP104 |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Application | |
---|---|
IHC | 1/25-1/100 |
ELISA | 1/5000-1/10000 |
The image is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using P06180(CEP104 Antibody) at dilution 1/25. (Original magnification: ×200) | |
The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P06180(CEP104 Antibody) at dilution 1/25. (Original magnification: ×200) |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
暂无评论
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
发表回复