Rabbit Polyclonal Antibody to CEP152

包装: 1G|100G|500G|1KG|100KG

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别名:centrosomal protein 152 kDa; centrosomal protein 152kDa; centrosomal protein of 152 kDa;
应用:IHC
反应种属:Human,Mouse
规格：50μl/100μl

Description
Necessary for centrosome duplication. Acts as a molecular scaffold facilitating the interaction of PLK4 and CENPJ, 2 molecules involved in centriole formation. Also plays a key role in deuterosome-mediated centriole amplification in multiciliated that can generate more than 100 centrioles. Overexpression of CEP152 can drive amplification of centrioles.Nagase T., DNA Res. 5:355-364(1998).The MGC Project Team; Genome Res. 14:2121-2127(2004).Andersen J.S., Nature 426:570-574(2003).

Description

Necessary for centrosome duplication. Acts as a molecular scaffold facilitating the interaction of PLK4 and CENPJ, 2 molecules involved in centriole formation. Also plays a key role in deuterosome-mediated centriole amplification in multiciliated that can generate more than 100 centrioles. Overexpression of CEP152 can drive amplification of centrioles.Nagase T., DNA Res. 5:355-364(1998).The MGC Project Team; Genome Res. 14:2121-2127(2004).Andersen J.S., Nature 426:570-574(2003).

Specification
Aliases	centrosomal protein 152 kDa; centrosomal protein 152kDa; centrosomal protein of 152 kDa;
Entrez GeneID	22995;
Swissprot	O94986
WB Predicted band size	140kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	Synthesized peptide derived from internal of human CEP152.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.