中文 
别名:Trh1; LASS4应用:WB,IHC
反应种属:Human
规格：50μl/100μl
| Description |
|---|
| The LASS (longevity assurance homolog) family members are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1, LASS2, LASS3, LASS4, LASS5 and LASS6) and they are all involved in sphingolipid synthesis. LASS4 is a 394 amino acid endoplasmic reticulum, multi-pass membrane protein. LASS4 increases the levels of long ceramides such as C22:0- and C24:0-ceramides. In cells deficient for CLN9, as observed in neuronal ceroid lipofuscinosis (NCL) or Batten disease, LASS4 can increase ceramide levels and partially correct growth and apoptosis. |
| Specification | |
|---|---|
| Aliases | Trh1; LASS4 |
| Entrez GeneID | 79603; |
| Swissprot | Q9HA82 |
| WB Predicted band size | 46kDa |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthetic peptide corresponding to a region derived from internal residues of human ceramide synthase 4 |
| Formulation | Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
| Application | |
|---|---|
| WB | 1/500-1/2000 |
| IHC | 1/50-1/200 |
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Gel: 8%SDS-PAGE Lysates (from left to right): Human fetal liver tissue, HT-29 and HUVEC cell, MCF-7 cell and human hepatocellular carcinoma tissue Amount of lysate: 40ug per lane Primary antibody: 1/300 dilution Secondary antibody dilution: 1/8000 Exposure time: 10 seconds |
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Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissue using P42939 at dilution 1/35. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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