Rabbit Polyclonal Antibody to CFH

包装: 1G|100G|500G|1KG|100KG

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别名:Complement factor H, H factor 1, CFH, HF, HF1, HF2
应用:WB
反应种属:Human
规格：50μl/100μl

Description
This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short concensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Description

This gene is a member of the Regulator of Complement
Activation (RCA) gene cluster and encodes a protein with twenty
short concensus repeat (SCR) domains. This protein is secreted into
the bloodstream and has an essential role in the regulation of
complement activation, restricting this innate defense mechanism to
microbial infections. Mutations in this gene have been associated
with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic
nephropathy. Alternate transcriptional splice variants, encoding
different isoforms, have been characterized.

Specification
Aliases	Complement factor H, H factor 1, CFH, HF, HF1, HF2
Entrez GeneID	3075
Swissprot	P08603
WB Predicted band size	139.1kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	This CFH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 751-780 amino acids of human CFH.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.