别名:Rab proteins geranylgeranyltransferase component A 2; Rab escort protein 2; REP-2; Choroideraemia-like protein;应用:WB,IHC
反应种属:Human
规格:50μl/100μl
Description |
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Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Less effective than CHM in supporting prenylation of Rab3 family.Cremers F.P.M., Hum. Mol. Genet. 1:71-75(1992).Kasper G., Gene 295:27-32(2002).Ota T. Nat. Genet. 36:40-45(2004) |
Specification | |
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Aliases | Rab proteins geranylgeranyltransferase component A 2; Rab escort protein 2; REP-2; Choroideraemia-like protein; |
Entrez GeneID | 1122; |
Swissprot | P26374 |
WB Predicted band size | 85kDa |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Synthesized peptide derived from internal of human CHML. |
Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Application | |
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WB | 1/500-1/3000 |
IHC | 1/50-1/100 |
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Western blot analysis of extracts from COLO cells, using CHML antibody P42541. |
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Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using CHML antibody P42541. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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