中文 
别名:D-10; CHRNA7; CHRNA7-DR1应用:WB,IHC
反应种属:Human,Mouse
规格：50μl/100μl
| Description |
|---|
| The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene, translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed. |
| Specification | |
|---|---|
| Aliases | D-10; CHRNA7; CHRNA7-DR1 |
| Entrez GeneID | 89832; |
| Swissprot | Q494W8 |
| WB Predicted band size | 46kDa |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Synthetic peptide corresponding to a region derived from internal residues of human CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion |
| Formulation | Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
| Application | |
|---|---|
| WB | 1/500-1/2000 |
| IHC | 1/25-1/100 |
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Gel: 10%SDS-PAGE Lysates (from left to right): Mouse liver tissue Amount of lysate: 40ug per lane Primary antibody: 1/700 dilution Secondary antibody dilution: 1/8000 Exposure time: 2 minutes |
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Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using P42870 at dilution 1/40. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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