Rabbit Polyclonal Antibody to CHSY1

包装: 1G|100G|500G|1KG|100KG

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别名:carbohydrate (chondroitin) synthase 1; chondroitin glucuronyltransferase II; chondroitin synthase; CHSS1; glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1
应用:WB,IHC
反应种属:Human
规格：50μl/100μl

Description
Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Involved in the negative control of osteogenesis likely through the modulation of NOTCH signaling.Kitagawa H., J. Biol. Chem. 276:38721-38726(2001).Nagase T., DNA Res. 6:63-70(1999).Clark H.F., Genome Res. 13:2265-2270(2003).

Description

Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Involved in the negative control of osteogenesis likely through the modulation of NOTCH signaling.Kitagawa H., J. Biol. Chem. 276:38721-38726(2001).Nagase T., DNA Res. 6:63-70(1999).Clark H.F., Genome Res. 13:2265-2270(2003).

Specification
Aliases	carbohydrate (chondroitin) synthase 1; chondroitin glucuronyltransferase II; chondroitin synthase; CHSS1; glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1
Entrez GeneID	22856;
Swissprot	Q86X52
WB Predicted band size	91kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthesized peptide derived from internal of human CHSY1.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Application
WB	1/500-1/3000
IHC	1/50-1/100

	Western blot analysis of extracts from HepG2 cells and K562 cells, using CHSY1 antibody P42356.
	Immunohistochemistry analysis of paraffin-embedded human brain tissue, using CHSY1 antibody P42356.