Rabbit Polyclonal Antibody to CIRBP

包装: 1G|100G|500G|1KG|100KG

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别名:CIRP
应用:IHC
反应种属:Human, Mouse, Rat
规格：50μl/100μl

Description
Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3′-untranslated regions (3′-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity). Promotes assembly of stress granules (SGs), when overexpressed.

Description

Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3′-untranslated regions (3′-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity). Promotes assembly of stress granules (SGs), when overexpressed.

Specification
Aliases	CIRP
Swissprot	Q14011
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse, Rat
Immunogen	Full length fusion protein
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
IHC	1/20-1/100
ELISA	1/5000-1/10000

	The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using P09511(CIRBP Antibody) at dilution 1/20. (Original magnification: ×200)
	The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P09511(CIRBP Antibody) at dilution 1/20. (Original magnification: ×200)