Rabbit Polyclonal Antibody to CKAP4

包装: 1G|100G|500G|1KG|100KG

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别名:p63; CLIMP-63; ERGIC-63
应用:WB,IHC
反应种属:Human, Mouse
规格：50μl/100μl

Description
CKAP4 (cytoskeleton-associated protein 4), also known as p63, CLIMP-63 or ERGIC-63, is a 602 amino acid single-pass type II transmembrane protein that links the endoplasmic reticulum (ER) to the cytoskeleton. Considered a novel protein in maintaining ER morphology, CKAP4 anchors the ER to microtubles which is required for maintaining ER spatial distribution during interphase of the cell cycle. CKAP4 can be reversibly palmitoylated and phosphorylated and is a major substrate of the palmitoyl acyltransferase, ZDHHC2.

Description

CKAP4 (cytoskeleton-associated protein 4), also known as p63, CLIMP-63 or ERGIC-63, is a 602 amino acid single-pass type II transmembrane protein that links the endoplasmic reticulum (ER) to the cytoskeleton. Considered a novel protein in maintaining ER morphology, CKAP4 anchors the ER to microtubles which is required for maintaining ER spatial distribution during interphase of the cell cycle. CKAP4 can be reversibly palmitoylated and phosphorylated and is a major substrate of the palmitoyl acyltransferase, ZDHHC2.

Specification
Aliases	p63; CLIMP-63; ERGIC-63
Swissprot	Q07065
WB Predicted band size	66 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse
Immunogen	Synthetic peptide of human CKAP4
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
WB	1/1000-1/5000
IHC	1/25-1/100
ELISA	1/2000-1/10000

	Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-3: 293T cells, hepG2 cells, A549 cells, Primary antibody: P11666(CKAP4 Antibody) at dilution 1/750, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
	The image is immunohistochemistry of paraffin-embedded Human lung cancer tissue using P11666(CKAP4 Antibody) at dilution 1/30. (Original magnification: ×200)